【摘要】 目的　研究脑缺血再灌注后迟发性神经元坏死（ Ｄ Ｎ Ｄ ）的病理学改变及测定病灶区 Ｃａ２ ＋ 含量的变化，并观察尼莫通对 Ｄ Ｎ Ｄ 的保护作用。方法　制作大鼠一侧大脑中动脉缺血再灌注模型。结果　当脑缺血 ６ ｈ 以上再灌流时 Ｄ Ｎ Ｄ 现象明显。结论　早期应用尼莫通治疗可使 Ｄ Ｎ Ｄ 减轻，起到神经元保护作用。更多还原

【Abstract】 The pathological change of delayed neuronal damage(DND) in focal ischemic reperfussion of cat cerebrum, and the regional distribution of tissure Ca 2+ contents were measured after the occlusion of middle cerebral artery(MCAO). Then Nimoton were used to alleviate the DND of the ischemic reperfussion. The results revealed that Nimoton is a better protector of ischemic brain damage.更多还原