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解脲脲原体血清型别与宫内感染的关系

Serotypes of ureaplasma urealyticum and intrauterine infection

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【作者】 周丽萍; 周洁; 徐肖文; 包其郁; 杨介钻; 陈素华; 谢爱兰;

【Author】 ZHOU Liping*, ZHOU Jie, XU Xiaowen, et al. * Department of Microbiology, Wenzhou Medical College, Wenzhou 325003

【机构】 温州医学院微生物学教研室;

【摘要】 目的研究解脲脲原体(Uu)血清型别与宫内感染的相关性。方法采用生长代谢抑制试验对28例胎膜早破(PROM)、早产组6例,正常妊娠(对照组20例)的宫颈分泌物、胎膜、脐带进行了Uu分离;并对分离的39株Uu菌株进行1~14型血清型别鉴定。结果早产组以4型占优势(60%3/5),PROM组以1型检出率最高(33.3%7/21)。早产组4型和1型的检出(57.7%15/26)较对照组(23.1%3/13)差异有显著意义(P<0.05);并证实从胎膜和脐带中检出的Uu菌株以4型和1型占主要优势(P<0.05)。结论解脲脲原体4型和1型与早产和胎膜早破密切相关

【Abstract】 Objective To evaluate the relationships between Ureaplasma urealyticum serotypes and intrauterine infection. Methods Serotypes of the U. urealyticum strains were detemined by a metabolic inhibition test. The serotypes of 39 U. urealyticum strains were obtained from the cervix, placenta membrane and umbilical cord in 28 PROM, 6 premature delivery patients (study group) and 20 nomal pregnant patients (control group). Results Serotype 4 was found in 60% of 5 patients with premature delivery, and serotype 1 in 33.3% of 21 patients with PROM. Serotypes 4 and 1 were isolated from 57.7% of the patients in the study group and from 23.1% of the patients in the control group (P<0.05). Serotypes 4 and 1 which were found more often in placenta membrane and umbilical cord than in the cervix (P<0.05). Conclusion U. uireatyticum serotypes 4 and 1 are closely associated with PROM and premature delivery.

【基金】 浙江省教委科研基金
  • 【文献出处】 中华医学检验杂志 ,Chinese Journal of Laboratory Medicine , 编辑部邮箱 ,1999年03期
  • 【分类号】R722.13
  • 【被引频次】32
  • 【下载频次】65
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