【摘要】 目的　观察和比较静脉注射地尔硫、毛花甙C控制快速心房颤动 (房颤 )和心房扑动(房扑 )心室率的即时疗效及安全性。方法　 5 4例快速房颤或房扑患者 ,采用随机方式分两组 ,分别静脉注射地尔硫、毛花甙C。结果　地尔硫、毛花甙C组控制房颤或房扑的快速心室率总有效率分别为 :94 %、70 % ,心室率平均下降幅度分别为 :3 4%、2 3 % ,平均起效时间分别为 :( 7 1± 4 2 )分钟、( 3 2 8± 2 2 8)分钟。地尔硫组出现可耐受性低血压 2例 ,发生窦性停搏 1例 ,均自行缓解 ,无心力衰竭加重表现。结论　静脉注射地尔硫能迅速、安全、有效地控制房颤、房扑的快速心室率。更多还原

【Abstract】 Objective To evaluate the efficacy and safety of intravenous diltiazem and cediland (lanatoside C) for treatment of rapid ventricular rate in atrial fibrillation and flutter Methods A single blind, randomized study on 54 patients with rapid atrial fibrillation and atrial flutter was conducted by comparing intravenous diltiazem and cediland (ratio 3:2) Results The total efficacies were 94% and 70% with a mean decrease in heart rate by 34% and 23% of the baseline in the diltiazem and cediland group, respectively, while mean time response to the bolus was 7 1±4 2 and 32 8±22 8 minutes, respectively Of the 34 patients treated with diltiazem, 2 developed asymptomatic hypotension and one had ventricular pause, all events were resolved without pharmacologic treatment No patient developed worsening of congestive heart failure due to diltiazem Conclusion Diltiazem is safe and rapidly effective in acutely slowing of rapid ventricular rate in patients with atrial fibrillution or atrial flutter更多还原