【摘要】 目的探讨对于临床上体检不能扪及而由Ｂ超检查发现的睾丸肿块的诊治方法。方法对有关病例的超声检查表现及其病理结果进行回顾性分析。结果近１０年来６００多例因各种原因行阴囊超声检查的患者中，共发现１４例１６处体检未能扪及的睾丸肿块。患者平均年龄４２４岁，肿块直径平均１２１ｍｍ，除１例外其余肿块均表现为低回声团块。所有病例均由手术病理检查证实，其中精原细胞瘤２例，淋巴瘤２例，睾丸囊肿和结核各２例，其余６例分别为胚胎癌、转移性腺癌、化脓性睾丸炎、睾丸纤维化、睾丸血肿、睾丸部分梗死等，其中恶性肿瘤６例。所有病例均行手术，其中１３例行高位睾丸切除，１例因行术中冰冻切片检查示良性囊肿而保留睾丸。结论对于Ｂ超检查偶然发现的睾丸肿块，仅仅依靠超声表现无法鉴别其良恶性，须结合患者的临床资料进行分析，除非有明显的炎症及外伤表现，否则对于不能确诊者均应经腹股沟切口进行探查，术中行冰冻切片检查可避免对良性病变进行不必要的睾丸切除，选择非手术治疗者应注意密切随访。更多还原

【Abstract】 Objective To find out the expression and significance of MXR7 mRNA in human hepatocellular carcinoma. Methods The 32 P labeled and purified PCR product of MXR7 cDNA was taken as probe. MXR7 mRNA expression was detected by Northern blot analysis in 30 samples of preoperatively untreated HCC and corresponding surrounding non cancerous hepatic tissue,and 12 normal liver tissues confirmed pathologocally. Results The frequency of MXR7 mRNA expression in HCC, the corresponding surrounding noncancerous hepatic, and normal liver tissues was 76 6%, 13 3% and 0, respectively. The frequency of MXR7 mRNA expression in HCC without serum AFP elevation and in HCC <5 cm was 9/10 and 5/6 respectively. Conclusions MXR7 mRNA over expression in human HCC is common and MXR7 mRNA may be expressed at early stage of HCC and can serve as tumor biomarker for HCC. The detection of MXR7 mRNA expression in liver puncture tissues may find small HCC without serum AFP elevation in the subclinical stage.更多还原