【摘要】 目的　探讨防治由围产因素造成的脑功能障碍的有效途径。　方法　新生儿缺氧缺血性脑病（ＨＩＥ）８２例，随机分为早期干预组与对照组。为使两组具有可比性，排除影响婴幼儿智能发育的有关生物及环境因素的差异。在患儿０～３岁的生长发育过程中，用丰富环境的教育活动促使脑功能得以改善并可望恢复正常。　结果　早期干预组经３年的训练，从第２年起就可看出，脑功能障碍病例明显少于对照组（Ｐ＜ ０．０５）。　结论　早期干预是防治围产因素脑功能障碍的较为有效的方法更多还原

【Abstract】 Objective To explore an effective way to prevent and treat brain dysfunction caused by some perinatal factors. Methods 82 Cases of HIE (Hypoxic Ischemic Encephalopath) and 24 LBW (Low Birth Weight) were divided into two groups randomy, the early intervention E 1 group( n =50) and control one ( n =53). The two groups were comparable. The differences of biological and environmental factors which could affect the intelligence development of infants were exclu ded, The babies of E 1 group were trained and educated in a rariaty of environment from 0 to 3 years of age. Results The cases brain dysfunction in the early intervention group that had been trained for three years became significantly fewer than those of the control group since the second year ( P< 0.05 ) Conclusion Early intervention is an effective way to the prevent and treat brain dysfunction caused by perinatal factors.更多还原