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分光光度法在诺西肽工业生产中的应用
APPLICATION OF SPECTROPHOTOMETRIC METHOD TO NOSIHEPTIDE PRODUCTION
【摘要】 讨论了微生物测定法和分光光度法两种方法测定诺西肽的含量。结果表明对诺西肽及其在发酵液和预混制剂中的测试,相关性良好,数理统计未见显著性差异。预混制剂中诺西肽含量≤150% 标示量时,其回收率可达95% ~105% 。
【Abstract】 Both microbiological method and spectrophotometry are described for assay of nosiheptide (1) and in its premixed preparation as well as culture broth. The results showed that both methods correspond well ( P >0.7). When the content of 1 in its premixed preparation is below 150% of labelled amount, the recovery of 1 is 95%~105%.
- 【文献出处】 中国医药工业杂志 ,CHINESE JOURNAL OF PHARMACEUTICALS , 编辑部邮箱 ,1999年12期
- 【分类号】TQ465
- 【被引频次】33
- 【下载频次】110