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放射加热疗治疗局部晚期非小细胞肺癌的研究
Hyperthermia Combined with Radiotherapy in the Treatment of Regional Advanced non Small Cell Lung Cancers
【摘要】 [目的]评价放射加热疗治疗局部晚期非小细胞肺癌(NSCLC)的疗效。(方法)采用随机配对的方法将不能手术的ⅢaⅢb。期NSCLC患者分为两组,A组采用放疗加热疗,B组单纯放疗。(结果〕A组和B组肿瘤有效率(C+PR)分别为91.18%、82.35%(P=0.05);A组急性放射反应和后期放射损伤较B组明显减轻(P值分别为0.03和0.035);3年生存率分别为11.76%和8.82%(P=00158),3年局控率为7.84%和5.88%(P=0.0398),3年无远处转移率分别为19.16%和18.42%(P=0.0213)。(结论)放疗加热疗治疗局部晚期NSCDLC疗效优于单纯放射治疗,且可减轻急性放射反应和后期放射损伤。
【Abstract】 To evaluate the rmCaCy of the hperthenda cedined with ndothmp in the bot of nded edvanced im edcell lung canan(NSde). [ Methods]The Patients with ortable NSCix of mp m.’ mb were whdrind into two gnpe: Gmp A: Thehyperthenda edined with edothempy op. Gmp B: The ndotheraPy alone gup. L ResultsJThe resmpes rate(CR + PR), 3-yun survivaltale disease be Iate and distant bos be the were 9l. l8%,82.35%(P = o.o5), ll .76%,8.82% (P = o.ol58),7.84%,5 .88% (P= o.o398)and l9. l6%, l8.42% (P = o.o2l3)in ~ A and ~ B ~vely.The arute tokicities and the late damag of taliothemp inthe grDUp A were less severe than that in the group B. [Conclusion]These data show that hyperthermia combined with ndotheIaPy is favorable int-t for ndonal advanced NSCre.
- 【文献出处】 中国肿瘤 ,BULLETIN OF CHINESE CANCER , 编辑部邮箱 ,1999年09期
- 【分类号】R734.2
- 【被引频次】10
- 【下载频次】52