【摘要】 目的探讨CA125在胸腔积液鉴别诊断中的作用。方法免疫放射分析法。结果1．结核性胸膜炎组、癌性胸腔积液组血清CA125水平均较正常对照组高，其中癌性胸腔积液组增高显著。2．以48U／ml为临界值，CA125诊断癌性胸腔积液的敏感度85．7％，特异度90．9％，准确度88．9％。结论血清CA125测定对于结核性胸膜炎与癌性胸腔积液的鉴别诊断具有重要的价值。更多还原

【Abstract】 Objective To investigate the role of CA125 in differential diagnosis of pleural effusion. Methods A twostep immunoradiometric assay. Results 1. In contrast to the normal control group, the level of serum CA125 in patients with tuberculosis pleuritis and malignant pleural effusion were higher, and the level of CA125 in patients with malignant pleural effusion was significantly higher than that in those patients with tuberculosis pleuritis. 2. As cut off value is 48U/ml, the sensitivity of serum CA125 assay in the diagnosis of maligant pleural effusion was 85. 7%, specificity 90. 9%, accuracy 88. 9%. Conclusion The assay of serum CA125 play an important role in the differential diagnosis of tuberculsis pleuritis and malignant pleural effusion.更多还原