【摘要】 目的　评价磁共振水分子扩散加权成像（ＤＷＩ） 在肝脏病变鉴别诊断中的价值。方法对１３ 例正常志愿者、２８ 例病人的腹部正常脏器以及３９ 例５９ 个病灶（ 肝癌７ 例１１ 个病灶，转移瘤１１例１９ 个病灶，海绵状血管瘤１３ 例１８ 个病灶，肝囊肿８ 例１１ 个病灶） 行ＤＷＩ并测量表观扩散系数（ＡＤＣ值） 。结果　正常肝、脾、肾、胆囊、胰腺及肌肉平均ＡＤＣ 值分别为０－６９ ×１０－３ ｍｍ２／ｓ、０－７１ ×１０－３ ｍｍ２／ｓ、１－６４×１０－ ３ ｍｍ２／ｓ、２－９２×１０－３ ｍｍ２／ｓ、０－８３×１０－３ ｍｍ２／ｓ、０－７３×１０－３ ｍｍ２／ｓ。肝囊肿、海绵状血管瘤、肝癌及转移瘤的平均ＡＤＣ值分别为３－０３×１０－３ ｍｍ２／ｓ、１－９１×１０－３ ｍｍ２／ｓ、０－９５ ×１０－３ ｍｍ２／ｓ、１－１８×１０－３ ｍｍ２／ｓ，囊肿、血管瘤及恶性肿瘤三者间有显著性差异（Ｐ＜０－００１）。结论　ＤＷＩ分析及ＡＤＣ值测量对肝脏局灶性病变鉴别诊断有一定价值，可作为肝脏ＭＲＩ的补充检查序列。更多还原

【Abstract】 Objective To determinetherole ofdiffusion weighted MRimaginginthe characterization of localliverlesions- Methods Diffusion weighted MRimaging and measurement of apparent diffusion coeffecient (ADCvalue) were performedin41 normalcasesand 39 patients with 59localhepaticlesions( hepaticcarcinoma 11,metastasis 19,hemangioma 18, hepatic cyst 11)- Results The mean ADCvalue of malignant masses (1-07×10-3 mm2/s) wassignificantlylowerthanthatofhemaniomas(1-91×10-3 mm2/s) and cysts(3-03× 10-3 mm2/s) ( P< 0-001) ,although the ADCvalues offew metastatic tumors overlaped with those of some hemangiomas- Conclusions Diffusion weighted MRimagingis usefulin differentiating hepatictumors,anditcan be accepted as a new sequenceinthecharacterization offocalliverlesions-更多还原