【摘要】 目的　探讨子宫内膜异位症（ 异位症） 与卵巢上皮性癌（ 卵巢癌） 的关系。方法　对３７１例卵巢癌中的２０ 例合并异位症的病例进行回顾性分析，并与３５１ 例未合并异位症的病例（ 其中内膜样癌３８ 例，透明细胞癌３９ 例） 进行对照研究。结果　２０ 例合并异位症者中，内膜样癌１１ 例，透明细胞癌７ 例，腺癌和浆液性乳头状腺癌各１ 例。合并异位症的卵巢癌与未合并异位症的同型卵巢癌相比较，前者细胞分化较好；应用 Ｋａｐｌａｎ Ｍｅｉｅｒ 法计算５ 年生存率，前者高于后者。结论　异位症与内膜样癌和透明细胞癌关系密切，异位症病灶恶变可能是这两型卵巢癌的来源之一。异位症手术后可行药物治疗，内膜样癌和透明细胞癌治疗时可考虑应用孕激素。更多还原

【Abstract】 Objective To analyse the relationship between endometriosis and epithelial ovarian cancer. Methods We analyzed retrospectively the 20 cases associated with endometriosis in 371 cases of epithelial ovarian cancer, and these 20 cases were also compared with the left 351 cases not associated with endometriosis(including endomtriod carcinoma 38 cases and clear cell carcinoma 39 cases). Results Among 20 cases, endomtriod carcinoma and clear cell carcinoma were most frequently associated with endometriosis, with 11 cases and 7 cases respectively, there was also 1 case of gland carcinoma and 1 case of serous papillary carcinoma. Cases of carcinomas associated with endometriosis had higher pathological grade and 5 year survival probability(Kaplan Meier method) than those cases not associated with endometriosis. Conclusions There is a close relationship between endometriosis and ovarian endomtriod carcinoma and clear cell carcinoma, the malignant transformation of endometriosis foci may be an important origin of them. Drug therapy is recommended for endomtriosis after the operation. In the treatment of endomtriod carcinoma and clear cell carcinoma, progestin can be used as an accessory method.更多还原