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早期喉癌与声带癌前病变的诊断和微创治疗

Minimally invasive treatment in early glottic cancer and vocal cord dysplasia

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【作者】 张小伯刘丹丹杨大章范为

【Author】 ZHANG Xiaobo, LIU Dandan, YANG Dazhang, et al China Japan Friendship Hospital,Beijing 100029

【机构】 北京中日友好医院耳鼻咽喉科

【摘要】 目的 对早期喉癌和癌前病变的临床诊断和病理诊断标准及微创伤治疗后的临床效果进行总结和探讨。方法 临床诊断并经病理证实的 3 2例早期声门癌 (T1N0 M0 )及 2 0例癌前病变在显微支撑喉镜下接受粘膜剥脱及声带切除与微波处理微创伤治疗。结果 经 3年随访 ,2 6例早期癌术后未见异常 ,3例复发 ,2例再次行剥脱术。 2 0例声带癌前病变分为声带白斑、轻度不典型增生、中度不典型增生、重度不典型增生。手术剥脱后经 3年随访无一例转为恶性。结论 ①早期喉癌和癌前病变的临床鉴别诊断非常重要 ,常常几种病理形态共存 ,过小的活检组织有漏诊之虞 ,采用剥脱手术 ,即是确切诊断的方法又是有效治疗的措施 ,并能恢复正常发音功能 ;②对于声带活动稍有减弱的声带肿瘤 ,其减弱原因可能与肿瘤重力压迫有关 ,不应放弃粘膜剥脱的微创性治疗 ;③手术后患者的密切随访是至关重要的

【Abstract】 Objective To investigate the pathologic and clinical diagnosis of early stage glottic carcinoma and the vocal cord dysplasia and the results of the minimally invasive treatment Methods Thirty two cases of early glottic cancer(T 1N 0M 0) and 20 cases of vocal dysplasia were treated with mucous stripping and minimally invasive cordectomy under the micro suspension laryngoscope The pathomorphology was observed with continuous sections Results After 3 4 years follow up, 26 cases of early glottic cancer remained tumor free, 3 cases relapsed and 2 cases received the re stripping operation twenty cases of vocal cord dysplasia were classified as: leucoplakia of vocal cord, mild atypical hyperplasia, moderate atypical hyperplasia and advanced hyperplasia None of them had malignant change after 3 years follow up Conclusion The laryngeal micro opreation under the micro suspension laryngoscope is an effective and safe cure procedure, it provides a definite diagnostic method for the early stage glottic carcinoma and the vocal cord dysplasia

  • 【文献出处】 中华耳鼻咽喉科杂志 ,CHINESE JOURNAL OF OTORHINOLARYNGOLOGY , 编辑部邮箱 ,1999年06期
  • 【分类号】R739.65
  • 【被引频次】47
  • 【下载频次】233
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