【摘要】 目的观察阿仑膦酸盐治疗原发性骨质疏松症患者的疗效、安全性和耐受性。方法对照观察阿仑膦酸盐使用６个月前后疼痛、骨密度、血常规、血生化、副作用等方面的变化。结果患者在３个月内疼痛缓解，全身各部位骨密度上升，其中男、女性腰椎总骨密度分别上升３．１％、３．５％，副作用轻微且多在用药初期即可自行缓解。结论阿仑膦酸盐治疗原发性骨质疏松症疗效好、安全、耐受性好更多还原

【Abstract】 Objective\ Investigating the effect, safety, and tolerance of alendronate on primary osteoporosis. Methods\ Comparing the changes in pain, bone mineral density (BMD),blood routine test, blood biochemistry, side effects etc. before and after 6 months of administration of alendronate. Results\ Pain of the patients were relieved in 3 months. BMD of major areas of total skeleton was increased, in which the total lumbar BMD of male and female patients were increased by 3.1% and 3.5%, respectively. The side effects were slight and disappeared in early stage of administration. Conclusion\ Alendronate is effective, safe and well tolerated in primary osteoporosis.更多还原