【摘要】 目的 :探讨壶腹周围癌的手术方式。方法 :对 10 5例壶腹周围癌患者行胰十二指肠切除术。结果 :1、3、5年生存率分别为 6 6 6 7% ,40 85 % ,2 5 0 0 %。影响术后远期疗效的主要因素有病程长短 ,肿瘤部位、大小 ;病理性质及组织来源 ,局部浸润和淋巴结转移状况。与患者的性别、年龄等因素无明显关系。结论 :在进一步探讨手术方式的基础上 ,深入了解壶腹周围癌分子生物学行为 ,提高早期诊断水平 ,加强辅助治疗 ,有望提高患者的生存率。更多还原

【Abstract】 From January 1980 to March 1996, 105 patients with peri-ampullary carcinoma underwent pancreaticoduodenectomy in our hospital The 1-, 3-and 5-year survival rates of these patients were 66 70%, 40 85%and 25 00%respectively Review and analysis of literatures and our data indicated that the factors influencing the long-term effect of surgery for periampullary carcinoma were the course of the disease, site of the tumor , pathological type, histologic source, local infiltration and lymphatic metastasis , while sex and age of the patient played a minor role in prognosis Therefore, it is expected to improve the survival rate through further understanding of moleculo-biological behavior of peri-ampullary carcinoma, early diagnosis and enhancing accessory therapy on the basis of modifying surgical technique更多还原