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五色灵芝对减轻鼻咽癌患者放疗反应及提高免疫功能的临床试验

Effect of Wuse - Lingzhi - Jiaonang on Reducing Side - effects of Radiotherapy .and Improving Immune Functionin Patients with Nasopharyngeal Cancer

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【作者】 莫浩元洪明晃张锦明陈德林马骏苏勇郭翔黄晓明邱枋李丽音

【Author】 Mo Haoyuan;Hong Minghuang;Zhang Jinming;et al(Department of ENT, Cancer Hospital, Sun Yat - sen University ofMedical Sciences, Cuangzhou)

【机构】 中山医科大学肿瘤医院鼻咽科!广州市510060中山医科大学肿瘤医院鼻咽?

【摘要】 观察由香港维特健灵健康产品公司提供的“五色灵芝胶囊”对减轻患者放疗反应及提高免疫功能的作用。方法:将确诊鼻咽癌进行单纯放疗的72例患者,随机分成试验组及对照组,每组各36例。在放疗期间试验组服五色灵芝胶囊2粒tid,而对照组服Vitc2粒tid。两组分别在放疗前、中、放疗后检测外周血淋巴细胞3H-TDR转化率,自然杀伤淋巴细胞,Hb、RBC、WBC及观察口干、胃纳、口腔粘膜反应。结果:试验组患者外周血3H-TDR淋巴细胞转化率白细胞的升高程度大于对照组,有显著性差异;其它指标两组间无差异。结论:“五色灵芝胶囊”对提高放疗患者的免疫功能有效,对减轻放疗副作用无效。

【Abstract】 Objective: To evaluate the effectiveness of Wuse - Lingzhi -Jiaonang on reducing ad-verse effects of radiotherapy and promoting the function of immune system in patients with nasopharyngealcancer (NPC) . Methods: A total of 72 patients with NPC who received radiotherapy were randomized in-to two arms treated ( n = 36) and control ( n = 36) . In the treated group Wuse - Lingzhi - Jiaonang wasadministered orally during radiotherapy while patients in the control group received vitamin C 600mg/day. The patients’ feeling of thirsty, appetite, buccal mucosa reaction, peripheral hemoglobin, RBC,WBC and converoion rate of lymphocytes, serous index of EB virus, NK cell levels before, during and af-ter medication were examined in both groups. Results: The conversion rate of WBC and lymphocyte weresignificantly higher in the treated group as compared with the control group, but the other parametersshowed no significant differences between these two groups. Conclusion: Wuse - Lingzhi - Jiaonang maybe helpful in improving the function of immune system in NPC patients receiving radiotherapy but it doesnot reduce the side effects of radiotherapy.

  • 【文献出处】 中国肿瘤临床 ,CHINESE JOURNAL OF CLINICAL ONCOLOGY , 编辑部邮箱 ,1999年03期
  • 【分类号】R284
  • 【被引频次】5
  • 【下载频次】159
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