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兔髂动脉血管内照射的实验方法
Research Method for Intra Arterial Irradiation in rabbit Restenosis Model
【摘要】 目的用改进型后装治疗机进行血管内放疗的可行性研究。资料与方法用兔髂动脉行血管成形术,制成血管狭窄模型,用改进型后装治疗机及微型放射源192Ir进行兔髂动脉内放疗,预防血管成形术后再狭窄。结果60只兔分为3组。1)放疗10Gy组;2)放疗18Gy组;3)对照组,只做球囊扩张血管损伤,不做放疗。放疗组及对照组均100%成功。结论改进型后装治疗机在兔髂动脉扩张术后照射,安全可行。
【Abstract】 Purpose To investigate the feasibility of the method for intra arterial irradiation in illiac arteries of rabbit.Meterials and Methods Flexible 192 Ir seed source inside a ballon catheter was inserted into the iliac artery of hypercholester rabbits olemic through the modified afterloading machine.Three dose schedules were studied:(1)10Gy;(2)18Gy;(3)control (nonirradiated).Results All iliac ateries were irradiated as successfully as expected.Conclusion Administration of intra arterial irradiation with 192 Ir Source is feasible and safety technically.
【Key words】 Branchtherapy Intra arterial Irradiation Prevention Restenosis after PTCA;
- 【文献出处】 中国肿瘤临床与康复 ,CHINESE JOURNAL OF CLINKAL ONCOLOGY AND REHABILITATION , 编辑部邮箱 ,1999年01期
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