【摘要】 目的：探讨可溶性细胞间粘附分子（ｓＩＣＡＭ－１）在急性脑血管病（ＡＣＶＤ）发生、发展中的作用。方法：采用酶联免疫吸附方法，测定６２例ＡＣＶＤ患者和２５例对照组血清ｓＩＣＡＭ－１的含量。结果：与对照组相比，ＡＣＶＤ血清ｓＩＣＡＭ－１含量均明显升高（Ｐ＜０．０１），动态观察显示，随着病情的好转，ｓＩＣＡＭ－１含量逐渐下降。ＡＣＶＤ患者头ＣＴ片病灶越大，ｓＩＣＡＭ－１含量升高也越明显。结论：血清ｓＩＣＡＭ－１含量的高低可作为判断ＡＣＶＤ患者病情变化的指标之一。更多还原

【Abstract】 Objective: Our objective was to understand the effect of soluble intercellular adhesion molecule1 (sICAM1) on formation and development process of patients with acute cerebrovascular disease(ACVD). Methods: Level of sICAM1 in serum was measured for 62 elderly patients with ACVD and 25 controls by enzyine linked immunosorbent assay (ELISA) method. Results: It was showed that the level of sICAM1 in the serum significantly increased for the patients, as compared with that for the controls (P<0.01). The sICAM1 levels in the serum for patients with cerebral hemorrhage and cerebral ischmia significantly decreased after treatment. There was correlation between the level of sICAM1 and sizes of focus in CT scan. Conclusion: It was suggested that sICAM1 could be one of the important parameters for clinical evaluation in patients with ACVD.更多还原