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脾栓塞治疗地中海贫血

TREATMENT OF SPLENIC EMBOLIZATION IN THALASSEMA

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【作者】 刘壮; 王琳琳; 廖清华; 沙林林; 黄丽莉; 廖宁; 陈国力; 李树全;

【Author】 Liu Zhuang, et al (Department of Pediatrics, First Affiliated Hospital, Guangxi Medical university)

【机构】 广西医科大学第一附属医院!邮编:530021; 广西柳州市人民医院;

【摘要】 采用脾栓塞治疗12例地中海贫血(地贫),其中重型β地贫6例,4例有效,贫血改善,2例疗效差,4月后又需定期输血,中间型a地贫6例,疗效显著,Hb维持>100g/L。治疗前后血清免疫球蛋白、T淋巴细胞亚群无明显变化,均在正常范围,而治疗前红细胞免疫功能低,治疗后恢复正常。说明脾栓塞是治疗地贫的有效方法。

【Abstract】 12 cases of thalassemia were treated with splenic embolization. Among 6 cases of 5 thalassemia major, 4 cases got a relative good effect that their anemia major, 4 cases got a relative good effect that their anemia were improved, and 2 cases got a poor effect that they hadto receive regular blood transfution. 6 cases of a thalassemia middle got a remarkable effectthat their hemoglobin concentration were over 100g/L. Compared pre-treating with treating,the variations of serum immunoglobulin concentration and T lymphocyte sub-groups had notsignificance. But the immune function of red blood cells was lower before treatment, and returned to normal after treatment.

【关键词】 地中海贫血; 脾栓塞; 治疗; 免疫;
  • 【文献出处】 中国小儿血液 ,China Child Blood , 编辑部邮箱 ,1999年04期
  • 【分类号】R725.5
  • 【被引频次】10
  • 【下载频次】45
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