【摘要】 为进一步确定中期孕母铁缺乏症对胎儿铁代谢的影响，我们研究了中期孕母与胎儿铁代谢的关系。结果发现，二者的红细胞碱性铁蛋白（ＥＦ）值是显著正相关关系（ｒ＝０．４０２１，Ｐ＜０．０２５），且孕母中度ＩＤＡ组胎儿ＥＦ值下降了１３．６％，而母、胎其它铁代谢指标间无相关关系；说明孕母铁缺乏影响其胎儿的铁储备，尤以严重铁缺乏时明显，证实孕母铁缺乏可致胎儿出生后易患铁缺乏症。更多还原

【Abstract】 The expression of ferritin receptor (FuR) on the human placental microvillous membrane in 30 cases mid-pregnancy and the variation in materal iron deficiency (ID) and irondeficiency anemia (IDA) were analysed by using the method of radioligand binding assaywith horse spleen 125I-apoferritin as radioligand. The results revealed that the expression ofFuR in normal placental microvillous membrane of mid-pregnancy was (9. 63±4. 72) × 1012sites/mg pro, similar to normal placenta of term delivery. In maternal occult ID and mildIDA, the FuR are significantly higher than the noraml (P<0. 05), whereas there are nodifference between the normal and the pregnant women suffered from moderate IDA. Theseshow that the FnR regulate maternal-foral iron metabolism by changing the amount of FuRexpression in pregnancy women with occult ID and IDA. However, the iron transferred frommother to fetal might be decreased when mother with moderate IDA.更多还原