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鸡溃疡性肠炎灭活苗的制备与应用研究

Preparation and Application of Oil emulsion Inactivated Vaccine against Ulcerative Enteritis in Chickens

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【作者】 刁有祥牛钟相张万福贾世玉

【Author】 DIAO Youxiang,NIU Zhongxiang,ZHANG Wanfu,JIA Shiyu (Shandong Agricultural university,Taian 271018)

【机构】 山东农业大学

【摘要】 用鹑梭状芽胞杆菌经福尔马林灭活后,与白油、司本80、吐温80,按一定比例混合后在胶体磨中快速乳化成油包水型,制备了鸡溃疡性肠炎灭活疫苗,经检测证明,该疫苗安全、可靠、稳定,4℃~8℃可贮存12个月,10℃~25℃可贮存3个月,注射后抗体效价可维持6个月,保护率可达100%。

【Abstract】 The oil emulsion inactivated vaccine against Ulcerative Enteritis were prepared by formalin in activated clostridium colinum with mineal oil and tween 80.The results of safety,efficacy and field tests showed that the vaccine had better immunogenicity and could be used safely and conveniently.It could be store at 4℃~8℃ for more than 12 months and 10℃~25℃ for more than 3 months.The protection rate was 100% and the duration of immunity last for 6 months.

  • 【文献出处】 中国预防兽医学报 ,CHINESE JOURNAL OF PREVENTIVE VETERINARY MEDICINE , 编辑部邮箱 ,1999年01期
  • 【分类号】S858.3,S855.3
  • 【被引频次】2
  • 【下载频次】38
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