【摘要】 目的了解2型糖尿病患者动态血压特点。方法按有无糖尿病和高血压分组，对408例受试者进行24小时动态血压监测。结果糖尿病伴高血压组平均收缩压及收缩压负荷大于平均舒张压及舒张压负荷略小于无糖尿病的原发性高血压组；糖尿病组无论是否伴有高血压，其昼夜血压差值均小于无糖尿病的二组。结论糖尿病组失去正常昼高夜低的血压波动规律，这种异常在患者未出现高血压时已经存在，提示糖尿病病人发生高血压的机理可能有别于非糖尿病者。对糖尿病者宜定期监测动态血压，并根据异常情况，在高血压出现之前即采取防治措施。更多还原

【Abstract】 Objective To investigate the characteristics of ambulatory blood pressure (ABP) profiles in type 2 DM.Methods To analyze and compare the results of 408 cases of ABP profiles among patients with or without diabetes andhypertension.Results The results showed that mean systolic blood pressure (BP) and systolic BP load were higher,while diastolic BP and diastolic BP load were lower in hypertensive diabetes than in primary hypertensive patientswithout diabetes. Diabetic:subjects with or without hypertension have much greater reduced BP day-night dip than thosewithout diabetes. Conclusion The results suggest that diabetic patients are likely to lose their normal diurnal BPrhythm even at the time when they are still normotensive. Therefore, the pathophysiology of diabetic hypertension isprobably somewhat different from non--diabetes. Patients with diabetes should have ABP monitoring periodically, in, order to detect abnormal changes in ABP profiles and take appropriate prophylactic measures before the occurrence ofhypertension.更多还原