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上海等四城市城区和郊区新生儿乙型肝炎疫苗免疫效果调查

An Investigation on Hepatitis B Vaccination of Newborns in four Provincial Capital Cities and Suburbs

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【作者】 贾志远武桂珍苏崇鳌黄玉英梨燕琴杨超美刘建地扈光伟刘崇柏

【Author】 JIA Zhi -yuan; WU Gui -zhen; SU Chong-ao; et al.( Institute of Virology, ChineseAcademy of Preventive Medicme. Beijing 100052, China.)

【机构】 中国预防医学科学院病毒学研究所!北京市100052中国预防医学科学院疾病控制处上海市卫生防疫站四川省成都市卫生防疫站甘肃省兰州市卫生防疫站吉林省长春市卫生防疫站中国预防医学科学院病毒学研究所!北京?

【摘要】 为了解乙型肝炎(乙肝)疫苗的免疫后效果,于1997年9~12月在上海、成都、兰州、肝春4个城市,采用整群随机抽样法抽取城区和郊区3~4岁儿童1271人调查,结果表明:1993~1994年新生儿乙肝疫苗接种丰城区为92.14%,明显高于郊区的76.97%。HBsAg阳性率降至2.28%,抗-HBS阳性率平均为71.28%.城区儿童未发现HBsAg阳性者,郊区儿童HBSAg阳性率为3.36%说明郊区是HBSAg阳性者的主要来源.此结果表明,我国乙肝疫苗免疫效果显著,但在郊区乙肝疫苗免疫工作有待加强。

【Abstract】 In order to investigate the effectiveness of the hepatitis B vaccination pro-grarnmes in different regions in China, a randomized sampling survey was carried out.A total of 1 271 children, aged 3 - 4 years old, were selected in 4 cities (Shanghai, Chengdu,Lanzhou and Changchun) during Sep. to Dec. 1997. The HB vaccine coverage rate in thecities (92.14%) was significantly higher than that in related suburbs (76.97%). The HBsAgcarrier rate decreased from 10% to 2.28% and anti - HBs positive rate was 71,28% in average.None of the HBsAg positive children was found in the cities, but in suburbs the carrier rate ofHBsAg was 3.36% among the children. Most unvaccinated children distributed in suburbsand they were the main source for HBsAg positive children. The effectiveness of hepatitis Bvaccine though was obvious, hut the vaccination prograhane should be strengthened in suburbs.

【关键词】 乙型肝炎疫苗接种乙型肝炎表面抗原
【Key words】 Hepatitis B vaccineVaccinationHBsAg
  • 【文献出处】 中国计划免疫 ,CHINESE JOURNAL OF VACCINES AND IMMUNIZATION , 编辑部邮箱 ,1999年05期
  • 【分类号】R186
  • 【被引频次】16
  • 【下载频次】43
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