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北京市崇文区健康人群麻疹抗体水平调查

Analysis of Immune Levels of Measies in Different Age Groups of Population in Chongwen District of Beijing

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【作者】 鲍亚范王幼兰高鹏胡玉清赵秀芬李学荣

【Author】 BAO Ya-fan; WANG You-lan; GAO Peng, et al. (Epidemic Prevontive Station of Chongwen District of Beijing, Beijing, 100050, China.)

【机构】 北京市崇文区卫生防疫站!北京市100050

【摘要】 为了解崇文区健康人群麻疹抗体水平,对0~49岁479人进行了麻疹抗体水平监测.结果显示,抗体阳性率为75.37%(361/479),阳性率较高的人群是1岁和20~29岁,分别是98.33%和93.33%;较低的是6月龄儿童,阳性率为1.69%.各年龄组间抗体阳性率的有极显著的统计学意义(P<0.001).从抗体水平看:以低抗体(1:200)为主,占44.68%,中抗体(1:800)占23.38%,高抗体(1:3200)占了30%;抗体几何平均滴度倒数(GRT)为246.72.抗体清度水平的的高低与阳性率分布一致,仍有24.64%的人处于易感水平,主要是6月龄儿童.这部分人群中有98.31%的人抗体水平<1:200.其中<1:50的占72.89%,1:50的占25.42%.经分析比较,其它年龄组抗体比较平衡稳定.因此今后预防的重点人群是6月龄儿童,建议麻疹疫苗(MV)初免提前至6月龄,并考虑可给婚前体检女青年进行MV免疫。

【Abstract】 This study investigated the measles immune level of 479 healthy people from 0 -49yeals old. The total antibody positive rate was 75.37% (361/479). The groups with higher antibodypositive rates were 1 year old (98.33%) and 20 year old (93.33%) persons, and that with lowest positive rate was 6 month old children (1.69%), the difference among them was very distinctive(p<0.001). The survey also showed that 44.68% of the populahon inveStigated was at a lowerantiboldy level, 23.38% at moderate level and 7.31% at higher level, the average GMRT was246.72. The antibody level was in accordance with the measles antibody positive rate. 24.64% of thepersons were susceptible to measles, they were mainly children of 6 months old, of them 98.31% hadantibody level < 1:50(72.89%) and 1:50 (25.42%) were involved. This study indicated that the 6month old childal were sensitive to measles, so we suggest that it is betthe to begin the primary~non of measles in children of 6 months old.

【关键词】 麻疹疫苗免疫水平监测
【Key words】 Measles vaccineImmune levelSurveillance
  • 【文献出处】 中国计划免疫 ,CHINESE JOURNAL OF VACCINES AND IMMUNIZATION , 编辑部邮箱 ,1999年04期
  • 【分类号】R511.1
  • 【被引频次】9
  • 【下载频次】27
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