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糖尿病空腹血糖诊断标准的探讨

Exploring Diagnostic Criteria of Fasting Plasma Glucose of Diabetes Mellitus

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【作者】 余勤王守俊董义光白悦心代敏佟之复杨泽

【Author】 Yu Qing,et al.,Depatment of Endocrinology,The First Affiliated Hospital,Henan Medical University(Zhengzhou 450052)

【机构】 河南医科大学第一附属医院内分泌科!郑州450052河南医科大学公共卫生学院卫生部北京医院

【摘要】 为探讨我国糖尿病空腹血糖的诊断标准,对1997 年郑州市40 岁以上经75g O G T T 检查的人群资料进行分析。 F P G 频数分析显示:新发现糖尿病组中 F P G≥78 m m ol/ L 仅占435 % ,正常组945 % F P G< 611 m mol/ L。在 F P G≥611~70 m m ol/ L 的177 例中,新发现 D M 占107 % , 正常者占588 % , I G T 者仅占305 % 。比较不同 F P G 水平被诊为 D M的危险性及误诊、漏诊率、特异性和敏感性表明,虽然 F P G≥70 m m ol/ L 与 F P G≥78 m m ol/ L 时相比被诊为 D M 的危险性稍有降低( 分别为9974 % 和9197 % ) ,诊断 D M 的特异性稍下降( 分别为999 % 和995 % ) , 误诊率稍有升高( 分别为0003 % 和737 % ) ,但漏诊率可由4750 % 降至3833 % ,敏感性可由降至435 % 明显提高到580 % 。而 F P G≥667 m m ol/ L 时诊为 D M 的危险性明显降至7662 % ,虽漏诊率可降至3483 % , 敏感性可提高到 638 % , 但误诊率明显 增高达23?

【Abstract】 Exploring the diagnositc criteia of fasting plasma glucose of diabetes mellitus in china.Form group of subjects;age≥40 years studied in Zhengzhou City’s epidemiological survey in 1997.Th esubjects who received 75g OGTT was analyzed,Result showed:The FPG distribution frequency in the DM group showed that only 43 5% of subjects had FPG≤7 8mmol.94 5% of subjects in the normal group had FPG<6 11mmol/L.Among 177 subjects who had FBG≥6 11~<7 0mmol/L,10 7% subjects had newly diagnosed DM,58 8% subjects were normal,and only 30 5%,subjects had IGT.considering different FPG,the subjects being the danger of DM,the rate of wrong diagnosis DM、the rate of missed diagnosis DM、the specificity and sensitivity were different.It truned out that the danger of DM and specifidcity of diagnosis were a little lower(99 74% and 92 97% respectively)(99 9% and 99 5% respectively) and the rate of wrong diagnosis of DM will be a little higher(0 003% and 7 37% respectively),qt the same time,the rate of missed diagnosis can be fallen dwn form 47 50% to 38 33% andthe sensitivity will go up form 43 5% to 58 0% clearly,when compared FPG≥6 67mmol/L with FPG≥7.8mmol/L.The danger of DM and the rate of missed diagnosis can be evidetly fallen down to 76 62% and 34 87%, respectively and sensitivity and the rate of wrong diagnosis will obviously go up to 63 8% and 23 33% separately,in the state of FPG≥6 67mmol/L.Result showed:The new criteria which was regarded FPG≥7 0mmol/L as normal criteria was put forward recently by ADA in America is still suitable in our country.examination of OGTT should be done for the subjects who had FPG≥6 11~<7 0mmol/L.

  • 【文献出处】 中国公共卫生 ,CHINA PUBLIC HEALTH , 编辑部邮箱 ,1999年09期
  • 【分类号】R587.1
  • 【被引频次】1
  • 【下载频次】71
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