【摘要】 目的研究硒对骨折愈合的影响。方法应用４０只家兔做成双侧肱骨中段实验性骨折，随机分为２组：对照组饲常规饲料；实验组每日加饲微量元素硒０６ｍｇ。术后２、３、４、５周取材，进行骨痂横截面积测量，光镜及电镜观察。结果实验组２～４周骨痂内的软骨细胞、成骨细胞等及基质的变化较对照组出现早，且功能活跃。结论饲料中加硒可促进兔骨折愈合，这可能与硒刺激软骨细胞的蛋白合成有关更多还原

【Abstract】 Objective To study the effect of trace element,selenium(Se)in the healing process of fracture.Methods Forty rabbits had been made experimental fractures at the middle shaft of the humerus bilaterally and divided into two groups randomly:the control group,fed with common forage;the experimental group,fed with Se(0 6mg/day)additionally.The specimens were taken out 2,3,4,and 5 weeks after operation,cross sections of the calluses were made to measure the area of the callus and to observe the structures with light and electron microscope.Results At 2 and 4 weeks,the appearance of chondrocyte and osteoblast and the changes of matrix in the callus of experimental group were much more earlier and the function of chondrocyte and osteoblast was more active.Conclusion Se added in forage could stimulate the synthesis of protein in chondrocyte to promote the healing of rabbits fracture.更多还原