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桂竹糖芥强心苷G对Na~+,K~+-ATP酶的抑制作用

Inhibitory Action of Cheiranthoside G on Na~+,K~+-ATPase

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【作者】 张晓丹; 季宇彬; 马瑛; 乔国芬; 孔琪;

【Author】 Zhang Xiaodan; Ji Yubin; Ma Ying; et al. (Department of Chinese Materia Medica, Heilongjiang Commercial College, Harbin 150076)

【机构】 黑龙江商学院中药系!哈尔滨150076; 黑龙江省计划生育药具站; 哈尔滨医科大学药理教研室;

【摘要】 对照哇巴因观察糖芥强心苷G对大鼠心肌ATP 酶活性的影响。结果表明糖芥苷G体外 显著抑制心肌Na~+,K~+-ATP酶,并呈浓度依赖性。而ATP对糖芥苷G的作用几无影响。

【Abstract】 The mechanism of inhibition of Na~+, K~+-ATPase by cheiranthoside G was studied. Characteristics of its inhibitory action of Na~+, K~+-ATPase were compared with those of ouahain. Results indicated that cheiranthoside G was a noncompetitive inhibitor with respect to Na+,K+, and the effect was dose dependent. ATP was without effect on Na+, K+-ATPase inhibition by cheiranthoside G’

【关键词】 糖芥苷G; Na~+; K~+-ATP酶; 抑制剂;
【Key words】 cheiranthoside G Na~+; K~+-ATPase;
【基金】 黑龙江省科委自然科学基金
  • 【文献出处】 中草药 ,CHINESE TRADITIONAL AND HERBAL DRUGS , 编辑部邮箱 ,1999年10期
  • 【分类号】R285
  • 【被引频次】3
  • 【下载频次】207
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