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滇白珠化学成分的研究(Ⅲ)

Studies on the Chemical Constiuents of Yunnan Wintergreen Root (Gaultheria yunnanensis) (Ⅲ)

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【作者】 张治针; 果德安; 李长龄; 郑俊华; 小池一男; 贾仲华; 二阶堂保;

【Author】 Zhang Zhizhen, Koike Kazuo, Guo Dean, et al. (Pharmaceutical College, Beijing University of Medical Sciences, Beijing 100083)

【机构】 北京医科大学药学院!100083; 日本东邦大学药学部;

【摘要】 从滇白珠Gaultheria yunnanensis(Franch.)Rehd.根的石油醚部分分得 10个化合物,其中8个化合物经理化性质和波谱分析,它们的结构分别鉴定为β-乙酰谷甾醇(Ⅰ),3β-乙酰基-12,25-二烯-达玛烷(Ⅱ),3β-乙酰氧基-20(29)-羽扇烯-28-醛(Ⅲ),3β-乙酰齐墩果酸(Ⅳ),β-谷甾醇(Ⅴ),熊果酸(Ⅵ),豆甾醇(Ⅶ)和3β-羟基-20(29)-羽扇烯-28-醛(Ⅷ)。其中Ⅱ为杜鹃花科植物中首次发现的达玛烷三萜类化合物,化合物Ⅰ、Ⅲ、Ⅷ为杜鹃花科植物中首次报道,其它4个化合物为从该植物中首次分得。

【Abstract】 Ten compounds were isolated from the petroleum ether fraction of the root of Gaultheria yunnanensis (Franch.) Rehd.. The structures of eight of them were identified as 3β-acetylsitosterol (Ⅰ ), 3β acety1-12, 25-dien-dammarane (Ⅱ ), 3β--acetoxy-20 (29) -lupen-28-aldehyde (Ⅲ ), 3β-acetyloleanoic acid (Ⅳ ), β-sitosterol (Ⅴ ), ursolic acid (Ⅵ ), stigmasterol (Ⅶ ) and 3β-hydroxy-20 (29)-lupen-28-aldehyde (Ⅷ ) by chemical and spectral methods. Among these compounds, Ⅱ is a dammarane triterpenoid discovered for the first time in Ericaceae; Ⅰ,Ⅲ andⅧ have not been reported previously from Ericaceae; the other four compounds were obtained from the title plant for the first time.

  • 【文献出处】 中草药 ,CHINESE TRADITIONAL AND HERBAL DRUGS , 编辑部邮箱 ,1999年04期
  • 【分类号】R284
  • 【被引频次】25
  • 【下载频次】368
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