【摘要】 目的：探讨蛇床果实种内香豆素成分的变异与地理分布的关系及其变异规律。方法：用毛细管ＧＣ 法对蛇床果实４８ 个居群５９ 个样品中蛇床子素、佛手柑内酯、欧前胡素、Ｏ乙酰哥伦比亚苷元等９ 个香豆素成分进行含量测定与定性分析。结果与结论：根据蛇床果实中香豆素成分化学结构的差异及各成分的有无与含量的高低结合地理分布，可将蛇床分为３ 个类型，即化学型Ｉ：以蛇床子素和线型呋喃香豆素为主要成分；分布于福建、浙江、江苏等亚热带常绿阔叶林区域。化学型ＩＩ：以角型呋喃香豆素为主要成分；分布于辽宁、黑龙江、内蒙古等温带针阔叶混交林区域。化学型ＩＩＩ：蛇床子素、线型和角型呋喃香豆素同时存在，属于混合的过渡类群；分布于河南、河北、山西等暖温带落叶阔叶林区域的过渡地带更多还原

【Abstract】 AIM: To find out the variation and regularity of coumarin constituents in Fructus Cnidii collected from different regions of China. METHODS: Capillary GC was applied to determine the contents of osthol, bergapten, isopimpinellin, xanthotoxin, imperatorin, O acetylcolumbianetin, columbianadin, cniforin A and edultin in the ethanol extracts of Fructus Cnidii of 59 samples collected from 48 populations of different geographical origins. RESULTS AND CONCLUSION: The results indicated that intra specific variation of coumarins in Cnidium monnieri fruits is related to the geographical distribution of the plants in China and the plant can be classified into three chemotypes: Chemotype 1: containing osthol as the main component and linear furanocoumarins, but no angular furanocoumarins, distributed in Fujian, Zhejiang, Jiangsu Provinces etc. in South China. Chemotype 2: containing no osthol but angular furanocoumarins as the main constituents, distributed in Liaoning, Heilongjiang, Inner Mongolia, etc. in Northeast China. Chemotype 3: an intermediate type, with the osthol content roughly inversely proportional to the angular furanocoumarins, distributed in Henan, Hebei, Shanxi, Shandong Provinces, etc. in a belt of transition between South and North China.更多还原