【摘要】 应用粘液组化方法观察了８１例直肠癌旁移行粘膜的变化规律，结果显示：癌旁移行粘膜的范围在粘液癌明显大于乳头状腺癌及管状腺癌，差异显著（Ｐ＜０．０１），ＤｕｋｅｓＣ期明显大于ＤｕｋｅｓＡ、Ｂ期，差别有显著意义（（Ｐ＜０．０１，Ｐ＜０．０５），不同分化程度的直肠癌之间，差别无显著意义（Ｐ＞０．０５）。结论：直肠癌旁移行粘膜与直肠癌的类型及进展密切相关。提示对粘液癌或ＤｕｋｅｓＣ期的低位直肠癌应严格掌握保肛手术适应症更多还原

【Abstract】 The changing character of the transitional mucosa(TM) adjacent to rectal carcinoma was investigated by mucinhistochemical method in 81 cases.The results showed that the range of TM in mucinous carcinoma was significantly larger than those in papilla adnoma and tubular adnoma(P<0.01).The range of TM in Dukes C stage was significantly larger than those in A B(P<0.01,P<0.05)。Conclusions:The range of TM was closely related to the pathological type and the advancement of rectal carcinoma.The results indicated that the indications for sphincter preserving operations should be strictly applied in rectal mucinous adnoma or rectal carcinoma in Dukes C stage.更多还原