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胆汁癌胚抗原诊断胆系良恶性病变的探讨

THE DIFFERENTIAL DIAGNOSTIC VALUE OF CEA IN BILE OF BENIGN AND MALIGNANT BILIARY DISEASES

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【作者】 霍景山; 孙作祥; 张蔚; 周健伟; 庞新华;

【Author】 Huo Jingshan, Sun Zuaxiang, Zhou Jianwei, et al. (Departement of Hepatobiliary Surgery, Affiliated Hospital of Ji Ning Medical College. Shangdong Province, 272129)

【机构】 济宁医学院附属医院!272129;

【摘要】 测定46例胆系病人的血清及胆汁癌胚抗原(CEA),发现胆石症与胆囊良性息肉胆汁及血清CEA水平均在15μg/L以下,统计学处理无意义。胆囊癌及胆管癌胆汁CEA水平均在20μg/L以上,明显高于血清CEA(P<0.01),且与胆石症及胆囊良性息肉胆汁CEA也存在非常显著差异(P<0.01),作者认为胆汁CEA测定可为临床鉴别胆系良恶性病变癌胚抗原提供一个较好的辅助诊断指标。

【Abstract】 Levels of carcinoembryonic antigen (CEA) in bile and serum were determined in 46 patients with biliary diseases. Benign biliary diseases including cholelithiasis and gallbladder polyp showed CEA values in bile and serum less than 15μg/L, wheras malignant biliary diseases including bile duct cancer and gallbladder cancer. CEA values in bile more than 20μg/L, higher than CEA valuer in serum (P<0.01), and higher than that of benign diseases(P<0.01). We think assessment of CEA level in bile would be a good indicator for differentiating benign and malignant biliary diseases.

【关键词】 胆汁; 胆系病变;
【Key words】 CEA Bile Biliary disease;
  • 【文献出处】 医师进修杂志 ,JOURNAL OF POSTGRADUATES OF MEDICINE , 编辑部邮箱 ,1999年04期
  • 【分类号】R575.6
  • 【被引频次】3
  • 【下载频次】22
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