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乙酰水杨酸对晶状体水合反应的影响作用
Effects of acetylsalicylic acid on hydration of galactose induced cataract
【摘要】 目的 评估乙酰水杨酸(ASA) 对半乳糖性白内障晶状体水合反应的影响作用。 方法 应用激光拉曼光谱分析技术(LRS) 和晶状体混浊度形态学记录(LOP) 分别从分子水平和临床形态学观察ASA 对大鼠半乳糖性白内障晶状体水合反应的影响作用。 结果 ASA 可降低半乳糖性白内障晶状体水合反应的程度,集中表现在以蛋白质变性为主导的后期核质混浊阶段。 结论 ASA 从细胞膜水平影响Na +/K+ 失衡,降低晶状体水合反应的程度
【Abstract】 ObjectiveTo evaluate the effects of acetylsalicylic acid(ASA)on hydration of galactose induced cataract in rats.MethodsLaser Raman Spectrometry(LRS)and lens opacity photography(LOP)were used to observe the effects of ASA on the development of galactose induced cataract.ResultsInhibitive effects of ASA on hydration of galactose induced cataract were demonstrated in the later stage of nucleus opacification.ConclusionASA can inhibit hydration of galactose induced cataract by affecting the balance of Na +/K + on the level of lens membranes.
- 【文献出处】 眼科研究 ,CHINESE OPHTHALMIC RESEARCH , 编辑部邮箱 ,1999年06期
- 【分类号】R776.1
- 【下载频次】24