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甲型与戊型肝炎的临床对比分析

Clinical comparison of hepatitis A with hepatitis E

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【作者】 尹华发许夕海叶英苏菲江福妹戚美芬

【Author】 Yin Huafa, Xu Xihai, Ye Ying et al (Dept of Infectious Diseases, The First Affiliated Hospital, Anhui Medcal University, Hefei 230022)

【机构】 安徽医科大学第一附属医院传染病科

【摘要】 目的比较甲型肝炎(甲肝)与戊型肝炎(戊肝)的临床特点。方法用ELISA法对755例肝炎患者进行甲、乙、丙、戊、庚型肝炎的病原学检测。结果甲肝和戊肝的检出率分别是111%和97%,差异无显著性(P>005);而两者在发病年龄、病程、总胆红素及与其他肝炎病毒的重叠或混合感染感染率方面差异有显著性(P<005或P<001)。结论与甲肝相比,该地区戊肝同样常见,戊肝具有发病年龄较大、黄疸较深、病程较长和与其他肝炎病毒重叠或混合感染率较高的特点。

【Abstract】 Objective To compare clinical characteristics in patients with hepatitis A with those of patients with hepatitis E. Methods Serologic markers of 5 kinds of hepatitis viruses were tested in 755 hepatitis patients with ELISA. Results Positive rates of anti HAV IgM and anti HEV IgM were 11 1% and 9 7% respectively. There was not significant statistical difference ( P >0 05). But there were significant differences between hepatitis A and hepatitis E in the age of attack, the course, total bilirubins and rate of co infection or mixed infection with other hepatitis viruses ( P <0 05 or P <0 01). Conclusion Hepatitis E was as common as hepatitis A in this area. Comared with hepatitis A the clinical characteristics of hepatitis E were as follows: older age of attack, more serious jaundice, longer clinical course and higher rate of co infection or mixed infection with other hepatitis viruses.

【关键词】 肝炎.甲型肝炎.戊型重叠感染
【Key words】 hepatitis Ahepatitis Esuperinfection
  • 【文献出处】 安徽医科大学学报 ,ACTA UNIVERSITIS MEDICINALIS NAHUI , 编辑部邮箱 ,1999年02期
  • 【分类号】R512.6
  • 【被引频次】1
  • 【下载频次】45
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