【摘要】 目的：探讨尼可刹米对结核性毁损肺呼吸衰竭的治疗效果。方法：３０例结核性毁损肺呼吸衰竭患者，先后于吸入２８％氧１小时后及静脉滴注尼可刹米加吸入２８％氧后分别测定其口腔阻断压（Ｐ０．１）、潮气量（ＶＴ）、每分钟通气量（ＶＥ）及动脉血氧分压（ＰａＯ２）、动脉血二氧化碳分压（ＰａＣＯ２）等指标。结果：静脉滴注尼可刹米后Ｐ０．１、ＶＥ、ＰａＯ２均显著增加，而ＶＴ、ＰａＯ２无显著变化。结论：尼可刹米对结核性毁损肺呼吸衰竭无确定的临床疗效。更多还原

【Abstract】 Objective:To evaluate the clinical effects of nikethamide therapy on pulmonary tuberculosis induced respiratory failure. Methods: Parameters such as mouth occlusion pressure(P 0 1),tidal volume(V T),each minute volume(V E),partial pressure of oxygen in artery (PaO 2),partial pressure of carbon dioxide in artery (PaCO 2) were detected respectively before and after using nikethamide and inhaling 28% O 2 in 30 cases with pulmonary tuberculosis induced respiratory failure. Results: Parameters such as P 0 1、V E and PaO 2 increased remarkably, while V T and PaCO 2 remained un change after using nikethamide. Conclusion: Nikethamide has no obvious effcet on respiratory failure caused by pulmonary tuberculosis.更多还原