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顺铂联合足叶乙甙治疗恶性胸腔积液60例

Results of Combination Therapy with Cisplatin plus Etoposide in the Treatment of Malignant Pleural Effusion in 60 Cases

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【作者】 楼耀璠;

【Author】 Lou Yaofan (The People’s Hospital of Dongyang City,Dongyang 322100)

【机构】 东阳市人民医院!东阳322100;

【摘要】 [目的]观察顺铂联合足叶乙甙联合治疗恶性胸腔积液的治疗效果。[方法]先将胸水尽量抽尽,将顺铂50mg,足叶乙甙100mg溶于生理盐水50ml,胸腔内缓慢注射。[结果]60例病人中,CR44例,PR9例,总有效率88.3%。[结论]顺铂联合足叶已甙胸腔化疗治疗恶性胸腔积液有效率高,毒副反应轻,是值得推广的疗法。

【Abstract】 Purpose]To evaluate the results of combination therapy with Cisplatin plus Etoposide in the treatment of malignant pleural effusion. [Methods]We performed pleurocentesis and drained out pleural effusion as much as opossible,then slowly injected Cisplatin 50mg and Etoposide 100mg which were dissolved in 50ml of natural sodium.[Results]In 60 evaluable cases,44 patients reached CR,9 patients reached PR, the overall response rate was 88.3%.[Conclusion] A high response rate was obtained in malignant pleural effusion treated by intrapleural injections of Cisplatin plus Etoposide.It is a promising therapy with minor toxicity.

  • 【文献出处】 浙江肿瘤 ,ZHEJIANG CANCER JOURNAL , 编辑部邮箱 ,1999年02期
  • 【分类号】R730.5
  • 【被引频次】3
  • 【下载频次】7
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