【摘要】 为了解高血压病人的血栓形成倾向，我们随机选取了４１例高血压病人及３４例正常血压者，分别观察了他们的纤维蛋白原及血浆组织型纤溶酶原激活物（ｔＰＡ）抗原及纤溶酶原激活物抑制物－１（ＰＡＩ－１）的含量。结果表明，高血压病人血浆纤维蛋白原水平无明显变化，但ｔＰＡ抗原含量减少，ＰＡＩ－１的水平增加。提示高血压病人存在内源性纤溶功能受损更多还原

【Abstract】 In order to study the ability to the thrombus formation,41 patients with essential hypertension and 34 patients with normotension were investigated.The plasma level of fibrinogen and tissue-type plasminogen activator(tPA) antigen and plasminogen activator inhibitor 1(PAI-1)antigen were determined.In comparing with normotensive subjects,essential hypertensive patients had higher plasma concentration of PAI-1 antigen(P>0.05)and lower plasma level of tPA antigen (P<0.05),but similar plasma level of fibrinogen(P>0.05).The results suggest that there is impaired fibrinolysis in patients with hypertension.更多还原