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四川彝族近亲婚配及其遗传学效应的调查
A SAMPLING STUDY ON CONSANGUINEOUS MARRIAGE AND ITS GENETIC EFFECTS IN THE YI NATIONALITY.
【摘要】 为了解彝族近亲婚配的现状,1994 年5月在四川省凉山彝族自治州进行了一次大规模抽样调查。六个县共调查彝族夫妇5142 对,其中近亲婚配576 对, 近亲婚配率为11.20% ;平均近交系数达70.62×10- 4 。调查仅见四种亲缘类型,三级亲属通婚占近亲婚配的99.2% ; 舅甥女婚配占近亲婚配的0.8% ; 两代连续近亲婚配占近亲婚配的41.32% 。近亲组流产率及死产率均高于非近亲组(P< 0.05),近亲组15岁以下子女遗传病及先天畸形的患病率也明显高于非近亲组(P< 0.01)。结果表明彝族农村地区近亲婚配仍较普遍, 直接影响到人口素质, 必须予以重视
【Abstract】 A sampling survey aimed at providing information on consanguineous marriage(CM) of the Yi nationality was carried out during May 1994 in Liangshan,Sichuan province.A total of 5142 couples in six counties were investigated,576 of them were proved to be of CM,the overall rate of CM was 11 20%.The mean inbreeding coefficient was 70 62×10 -4 .CM identified in the survey can be divided into four types.99 2% of CMs occurred in first cousins.In addition,a rare type of CM(e.g.marriage between uncle and niece) was also found in remote villages of Butuo county,accounting for 0 8% of CMs.41 32% of CMs were consecutive CM within two generations.It was observed that both abortion rate and still birth rate in CM group were significantly higher than those in non CM group( P <0 05).Moreover,a significant difference in the prevalence rate of genetic diseases and congenital malformations between the two groups was observed among children under age 15( P <0 01).In conclusion,this study suggests that CM remains common in the rural areas of the Yi nationality and it has become one of the major factors which directly affect population quality of these areas,great attention should be paid to it.
- 【文献出处】 现代预防医学 ,MODERN PREVENTIVE MEDICINE , 编辑部邮箱 ,1999年04期
- 【分类号】R169.1
- 【被引频次】1
- 【下载频次】41