【摘要】 目的　探讨口腔扁平苔藓的免疫发病机理。方法　透射电子显微镜。结果　活化的 Ｔ 淋巴细胞攻击粘膜上皮细胞； 上皮基底板呈间断性断裂；肥大细胞增生、活化、脱颗粒、溶解； 粘膜固有层淋巴细胞带状浸润，可见淋巴细胞间合作现象； 微血管内皮细胞及周细胞损害； 微血管基底板高度增厚， 显示有免疫沉积物； 粘膜上皮凋亡； 郎格罕细胞变化。结论　进一步证实口腔扁平苔藓是以细胞介导的免疫反应为主。更多还原

【Abstract】 Objective\ To investigate the immunopathogenesis of oral lichen planus.Method Transmission elecron microscope.Result Activated T lymphocytes attack epithelial cells;basement membrane fragmentation and breakdown;proliferation、activation,degranulation and cytolysis of mast cellular cooperation;damage of the microvascular endothelial cells and perithelial cells;microvascular basal lamina severely thicken and show deposition of immunocomplex;intra epithelial cells exhibite apoptosis;degeneration of Langerhans cells.Conclusion Cell mediated immune reaction predominating in oral lichen planus has been confirmed.更多还原