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三种助孕技术治疗多囊卵巢综合征不孕的疗效比较

The comparison of the results of three kinds of assisted reproductive technologies for the treatment of sterility patients with polycystic ovarian syndrome.

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【作者】 李媛冯云陈子江

【Author】 Li Yuan 1,2 ,Feng Yun 2,Chen Zijiang 1,2 1Shandong Medical University,250012 2 Reproductive Medical Center of Shandong Provincial Hospital,250021

【机构】 山东医科大学!25001山东省立医院生殖医学中心

【摘要】 目的:观察3种助孕技术:IVFET、GIFT和控制性超促排卵(COH)后自行同房对多囊卵巢综合征(PCOS)不孕患者的疗效。方法:应用3种方法治疗,观察各组的临床妊娠率和发生卵巢过度刺激综合征(OHSS)的情况。结果:IVFET和GIFT与COH相比能得到更高的临床妊娠率,而前二者发生OHSS的危险性明显低于后者。结论:为避免COH后发生OHSS,建议对因PCOS不孕的患者采取体外助孕技术治疗。应用何种技术要根据患者的具体情况而定。如果有至少1 条输卵管完全正常,可先试行GIFT。此外,须将多余的卵子进行体外授精试验,观察其受精及卵裂情况,从而对今后的治疗提出指导性建议,并要将得到的胚胎进行冷冻保存,以备今后使用。

【Abstract】 Objective:To compare the three assisted reproductive technologies(IVF ET,GIFT and COH)for the treatment of patients with PCOS.Methods:The above mentioned three methods were used to treat 3 groups of PCOS patients separately.The clinical pregnancy rates and the occurrence of OHSS in each group were observed.Results:IVF ET and GIFT could achieve higher success than COH for the treatment of PCOS,and the risk of OHSS was much lower than that in the later.Conclusions:Avoiding the risk of OHSS,IVF ET or GIFT is the favorable protocol to be chosen.If the patient has at least one absolutely normal fallopian tube,it’s better to choose GIFT as the first line treatment method,and the excess oocytes should be ferformed invitro fertilization test.Thus,it will be a guidance to the treatment of that woman in the future,and the acquired embryo ought to be preserved by freeze for future application.

【基金】 山东省科委资助项目及卫生部青年科学基金
  • 【文献出处】 现代妇产科进展 ,CURRENT ADVANCES IN OBSTETRICS AND GYNECOLOGY , 编辑部邮箱 ,1999年03期
  • 【分类号】R711.605
  • 【被引频次】1
  • 【下载频次】104
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