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铝对体外培养小鼠卵母细胞减数分裂的影响
Effect of aluminium on meiotic maturation of mouse oocyte in vitro
【摘要】 本实验采用小鼠卵母细胞体外培养的方法研究了3~60m g/ L 的硝酸铝对小鼠卵母细胞减数分裂的影响。结果表明,铝对卵母细胞生发泡破裂( G V B D)没有影响,但可以抑制卵母细胞第一极体的排出,30m g/ L和 60m g/ L的两个剂量组可降低卵母细胞的存活率。实验结果提示铝对小鼠卵母细胞的减数分裂有破坏作用。
【Abstract】 The effect of aluminium nitrate on the meiotic maturation of mouse oocyte was studied in the culture of mouse oocyte. The results showed that aluminium nitrate could inhibite the extruding of the first polar body and the dose of 30mg/L and 60 mg/L could affect the viability of mouse oocyte, but little impact on the germinal vesicle breakdown(GVBD) of oocyte. The results indicated that aluminium nitrate might be hazardous to the meiotic maturation of mouse oocyte.
【基金】 扬州大学科研基金
- 【文献出处】 卫生研究 ,JOURNAL OF HYGIENE RESEARCH , 编辑部邮箱 ,1999年05期
- 【分类号】R114
- 【被引频次】38
- 【下载频次】165