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7起乙型脑炎疫苗异常反应的调查和分析

A survey and analysis of seven cases of adverse reactions after Japanese encephalitis vaccination

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【作者】 李雪翔谢广中

【Author】 Li Xuexiang,Xie Guangzhong.(Shanghai Institute of Biological Products,Shanghai 200052)

【机构】 卫生部上海生物制品研究所

【摘要】 对1993~1997年间因接种乙脑疫苗引起的7起异常反应进行了调查和分析,主要是Ⅰ型变态反应(0.33%~1.6%)和心因性反应(11.7%~24.2%)。反应一般发生在第3针以后,有些发生在第6针。症状表现为过敏性休克、紫癜、荨麻疹、血管神经性水肿、气喘等。对变态反应的发生频率、反应机理、处理方法和预防等问题进行了讨论

【Abstract】 Seven cases of adverse reactions including type Ⅰ allergic reactions (0.33%~1.6%)and psychogenic reactions(11.7%~24.2%).After Japanese encephalitis vaccination in the period between 1993~1997 were surveyed and analysed.These reactions were mostly seen after the third vaccination,and some Were after the sixth.The reactions were manifested by allergic shock,purpura,urticaria and angioedema.The frequency,treatment,mechanism and prevention of allergic reactions after Japanese encephalitis vaccination are discussed.

  • 【文献出处】 微生物学免疫学进展 ,PROGRESS IN MICROBIOLOGY AND IMMUNOLOGY , 编辑部邮箱 ,1999年01期
  • 【分类号】R595.3
  • 【被引频次】6
  • 【下载频次】60
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