【摘要】 １１０ 例伴有呼衰和心衰的慢性肺心病（ Ｃ Ｐ Ｈ Ｄ） 者随机分为观察组（６０ 例） 和对照组（５０ 例） ，对照组采用常规治疗，观察组在常规治疗的基础上加用苄胺唑啉（ Ｐ Ｈ Ｌ） 、多巴胺（ Ｄ Ａ） 及卡托普利（ Ｃ Ｐ） 。通过对两组病人的临床和动脉血气的监测发现：扩血管治疗既可显著提高常规治疗的疗效（ Ｐ＜ ００５） ，还可通过促进心肺功能的改善，显著升高 Ｐａ Ｏ２ ，降低 Ｐａ Ｃ Ｏ２（ Ｐ 均＜ ００５） ；未见明显不良反应。更多还原

【Abstract】 To evaluate the effect of vasodilator therapy on severe cor pulmonale ,the clinical phenom ena andarterial blood gas levels were studied in 110 patients with severe cor pulm onale acco m panied by respiratoryfailure and heart failure . Sixty of the m were treated with phentolamine ,dopa mine and captopril on top ofroutine treatment . The results show ed that vasodilator therapy dram atically raised the therapeutic effect ofroutine treatment ( P < 0 .05) , Pa O2 was increased rem arkably ( P < 0 .05) and Pa C O2 w as reducedmarkedly( P< 0 .05) due to im prove ment of the cardiac and pulm onary function . No significant side effectof vasodilator was observed . These findingsindicate that vasodilator therapy is an effective and safe m ethodfor severe cor pulm onale .更多还原