【摘要】 评价准分子激光原位角膜磨镶术（ＬＡＳＩＫ）的治疗效果和安全性。方法：采用ＬＡＳＩＫ技术对高度近视（Ａ组）和超高度近视（Ｂ组）进行手术并对手术效果进行对比分析。结果：Ａ组屈光度由术前等效球镜（－８．３５± ０．５）Ｄ减少到术后（－ ０．６１± ０．４４）Ｄ，Ｂ组由（－１２． ５５± ２．８２）Ｄ减少到（－１．２８±０．８）Ｄ。与术前相比，差别有统计学意义（Ｐ＜０．０５）。裸眼视力≥０．５和≥１．０者Ａ组分别是１００％和３２．９％，Ｂ组分别是８９．１４％和２１．７％。两组间比较，差别有统计学意义（Ｐ＜ ０．０５）。合并症术中有角膜刀中途停顿，角膜缘少量出血及术后偏中心等。结论：ＬＡＳＩＫ手术对高度和超高度近视有良好矫治效果。但手术复杂，手术参数和远期效果需要进一步探讨。更多还原

【Abstract】 Objective: To evaluate the efficacy and safety of a recent technique of laser in situ keratomileusis (LASIK) for correction of high and extra-high myopia. Method:The results of initial 199 eyes that underwent LASIK with the Chiron Automated Corneal Shaper and the Nidek laser were studied and the myopic eyes were divided into group A (high myopia) and group B (extra-high myopia). Results:Group A had a mean preoperative spherical equivalent refraction of (-8.35± 0.5)D and mean postoperative refraction of (- 0.61± 0.44)D, group B had preoperative refraction of (-12.55 ± 2.82)D and (-1.28 ± 0.8)D postoperatively (P<0.05). The uncorrected visual acuity was 0.5 or better and 1 .0 or better in 100% and 36.99% for group A and 89. 14%,21 .99% for group B(P<0.05). Complications included failure of the keratome to make a cut, excessive thin cap, minor corneal bleeding interoperatively, and excessive central, lipid deposits etc.postopera- tively. Conclusion: LASIK can be an effective method for reducing high and extra-high myopia with minimal complications. It is more complicated than PRK and more dependent on the surgical skills. Current surgical algorithms need modification, and the stability requires further study.更多还原