【摘要】 为明确金黄色葡萄球菌肺炎的发病现状、对抗生素的敏感性和影响预后的因素，回顾分析了同济医院内科呼吸病房１９８４～１９９７ 年住院金葡菌肺炎患者１０８ 例的发病、抗生素敏感性和预后情况。结果显示患者平均年龄１６．８±１２．５ 岁， 男性多见， 临床表现无特殊性， 以发热、脓痰、胸痛为多见； 可同时出现脓胸或脓气胸、身体其它部位脓肿形成等多种并发症并影响患者预后。金葡菌对抗生素的敏感性出现一定变迁， 且具有多重耐药性； 预后与住院天数、退热前有效的抗生素应用呈正相关， 而与发热天数、胸痛以及感染来源呈负相关。表明金葡菌肺炎临床表现无特殊性， 并发症出现率高， 细菌具有多重耐药性， 及早足疗程应用有效抗生素能改善疾病预后更多还原

【Abstract】 To elucidate the m orbidity, the sensitivity to the antibiotics and the factors influencing the prognosis of staphylococcus aureus pneum onia (SAP), the retrospective analysis of the m orbidity, the sensitivity to the antibiotics and the factors influencing the prognosis ofthe hospitalized patients w ith SAP w as carried out during 1984- 1997. The results dem onstrated that the patients w ith SAP, 16.75±12.45 years old, had no typicalclinicalfeatures butfever, purulentsputum and chestpain, and the accom panied diseases such as em pyem a, purulentpneum othorax and abscessofthe rem ote organs w ere found in m ostof the patients,w hich m ay also w orsen the prognosis ofthe patients. Staphylococcusaureuscultured from the patients had m ultiple resistance to antibiotics, and spectrum of the drugs sensitive to the bacterium w as gradually changed w ith the decades. The prognosis w ere positively relative to the duration of hospitalization, the use ofeffective antibiotics, and negatively relative to the days w ith feverand chestpain and the origin of the infection. It could be concluded that the patients w ith SPA had no typical clinical features, and usually had serious accom panied diseases. The pathogens had m ultiple resistance to antibiotics. The full- duration use of sensitive antibiotics as early as possible can considerably contribute to the prognosis of the disease.更多还原