节点文献
溃疡愈合宁药效学研究
Studies on the Pharmacodynamics of Ulcerous Recover Calm
【摘要】 对大鼠醋酸型、小鼠幽门结扎型及利血平型胃溃疡模型的药效实验证实:溃疡愈合宁对胃溃疡有显著的治疗作用。对大鼠结扎幽门胃液分泌影响实验表明:溃疡愈合宁中、小剂量组能显著增强胃液中胃蛋白酶活性,抑制总酸排出量。小鼠的镇痛及断尾止血实验证明:溃疡愈合宁三个剂量组均有止痛止血作用
【Abstract】 Through the pharmacodynamical experiments on the gastric ulcerous models of acetic acid-induced rats,plylorus-Ligation and reserpin-induced mice, Ulcerous Recover Calm was proved to have significant therapeutic effects on gastric ulcer.The experiments of gastric juice secretion on plylorus-Ligation rats showed:Middle and low dose groups of the drug significantly increased pepsinase activity in gastric juice,inhibited the total acids drainage.The experiments of mice analgesia and tail-cut hemostasis confirmed:three dose groups of the drug all had analgestic and hemostatic effects.
【Key words】 Gastric ulcerous model; Gastric juice secretion; Analgesia; Hemostasis;
- 【文献出处】 时珍国医国药 ,LiShiZhen Medicine and Materia Medica Research , 编辑部邮箱 ,1999年12期
- 【分类号】R286
- 【被引频次】6
- 【下载频次】47