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溃疡愈合宁药效学研究

Studies on the Pharmacodynamics of Ulcerous Recover Calm

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【作者】 谭宫屏; 曹华; 万军梅; 熊建平; 邢素兰; 李乐真;

【Author】 Tan Gongping, Cao Hua, Wan Junmei, et al Institute of Integrated Traditional Chinese and Western Medicine,Hubei Provincial Academy of Traditional Chinese Medicine,Wuhan 430074

【机构】 湖北省中医药研究院中西医结合研究所!湖北武汉430074; 湖北?;

【摘要】 对大鼠醋酸型、小鼠幽门结扎型及利血平型胃溃疡模型的药效实验证实:溃疡愈合宁对胃溃疡有显著的治疗作用。对大鼠结扎幽门胃液分泌影响实验表明:溃疡愈合宁中、小剂量组能显著增强胃液中胃蛋白酶活性,抑制总酸排出量。小鼠的镇痛及断尾止血实验证明:溃疡愈合宁三个剂量组均有止痛止血作用

【Abstract】 Through the pharmacodynamical experiments on the gastric ulcerous models of acetic acid-induced rats,plylorus-Ligation and reserpin-induced mice, Ulcerous Recover Calm was proved to have significant therapeutic effects on gastric ulcer.The experiments of gastric juice secretion on plylorus-Ligation rats showed:Middle and low dose groups of the drug significantly increased pepsinase activity in gastric juice,inhibited the total acids drainage.The experiments of mice analgesia and tail-cut hemostasis confirmed:three dose groups of the drug all had analgestic and hemostatic effects.

  • 【文献出处】 时珍国医国药 ,LiShiZhen Medicine and Materia Medica Research , 编辑部邮箱 ,1999年12期
  • 【分类号】R286
  • 【被引频次】6
  • 【下载频次】47
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