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用乳状液膜法从发酵液中提取青霉素G
Extraction of Penicillin G from Fermentation Liquor by the Emulsion Liquid Membrane Method
【摘要】 用乳状液膜法从青霉素发酵液中提取了青霉素G.着重研究了外相缓冲液、膜相有机溶剂、内相Na2CO3溶液的浓度、载体种类及用量、提取时间对提取率的影响,从而确定了各影响因素的最佳值.提取率可达655%.
【Abstract】 TheextractionofpenicillinGfromfermentationliquorbyanemulsionliquidmem branemethodwasstudiedundervariousoperationalconditions.Thesuitablebuffersolution ,the suitableorganicsolventandcarrierforsuchsystemswerederived .Thesewerecitratebuffersolu tion ,keroseneandtrioctylamine .TheeffectsofNa2 CO3 concentrationintheinternalaqueoussolu tion ,carrierconcentrationandextractiontimeonthetransportrateofPenGbytheemulsionliq uidmembranemethodwerealsooptimizedrespectively .Theextractiondegreeof 65 5%wasob tainedunderappropriateconditions.
- 【文献出处】 沈阳药科大学学报 ,Journal of Shenyang Pharmaceutical University , 编辑部邮箱 ,1999年04期
- 【分类号】R914
- 【下载频次】120