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自体外周血干细胞移植中造血干细胞的程控冷冻与液氮保存的初步研究

Preliminary Study on the Programmed Freezing and Liquid Nitrogen Preservation of Autologous Peripheral Blood Hematopoietic Stem Cells

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【作者】 常伟荣; 夏学鸣; 吴德沛; 岑建农;

【Author】 Chang Weirong,Xia Xueming,Wu Depei,et al (Department of Hematology,First Hospital Affiliated to Suzhou Medical College,Suzhou,215006)

【机构】 江苏省血液研究所; 苏州医学院附属一院血液科!苏州; 215006;

【摘要】 14 例自体外周血干细胞移植中,用程控冷冻仪冷冻、液氮保存造血干细胞,在病人预处理方案结束后,经静脉回输复苏之造血干细胞。结果:细胞植活及造血功能恢复良好,中性粒细胞> 0 .5 ×109 / L,平均为11 天, Plt> 30 ×109 / L,平均为21 天。

【Abstract】 The peripheral blood hematopoietic stem cells from 14 patients receiving autologous peripheral blood stem cell transplantation underwent programmed freezing and liquid nitrogen preserving.After conditioning regimen,the recovered stem cells were infused through vein,and hematopoietic reconstitution was good.The concentration of neutrophil was over 0.5×10 9/L and platelet over 30×10 9/L,and the survival time in average for neutrophil and platelet was 11 and 21 days respecticely.

  • 【文献出处】 苏州医学院学报 ,ACTA ACADEMIAE MEDICINAE SUZHOU , 编辑部邮箱 ,1999年09期
  • 【分类号】R457
  • 【被引频次】1
  • 【下载频次】53
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