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腺苷脱氨酶和结核抗体的测定对诊断结核性腹水的临床价值
The tests of ADA and anti-TB in ascites in diagnosis of tuberculous ascites.
【摘要】 目的寻找对结核性腹水高敏感、高特异而又简单的检查方法。方法采用改良的Martineck法和ELISA法对50例结核性腹水腺苷脱氨酶(ADA)和结核抗体水平进行了检测,并以45例恶性腹水和30例肝硬化腹水作对照。结果结核性腹水ADA和结核抗体水平显著高于对照组(P<001)。以ADA>30U/L作为阳性标准,其对结核性腹水的敏感性为100%,特异性为986%,准确性为992%;结核抗体对结核性腹水的敏感性为90%,特异性为933%,准确性为92%。结论ADA和结核抗体对诊断结核性腹水均有重要价值。在使用抗结核药特别是在并用激素治疗后,腹水ADA及结核抗体水平会随之下降,故应在停药1周后检测并动态观察二者的变化。
【Abstract】 Objective\ To seek better diagnostic tests for tuberculous ascites. Methods\ Adenosine deaminase (ADA) and anti-TB in ascites were tested by modified Martineck’s method and ELISA in 50 cases of tuberculous ascites,45 cases of carcinous ascites and 30 cases of cirrhotic ascites,respectively. Results\ The level of ADA and anti-TB in ascites was remarkably higher in tuberculous ascites than that in carcinous ascites and cirrhotic ascites (P<0.01).When ADA>30U/L and positive anti-TB were present,their sensitivity,specificity and accuracy in diagnosis of tuberculous ascites are 100%,98.6%,99.2% and 90%,93.3%,92%,respectively. Conclusion\ The tests of ADA and anti-TB in ascites are very important in diagnosis of tuberculous ascites.
- 【文献出处】 中国实用内科杂志 ,CHINESE JOURNAL OF PRACTICAL INTERNAL MEDICINE , 编辑部邮箱 ,1999年07期
- 【分类号】R446.9
- 【被引频次】30
- 【下载频次】84