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SLE患者血清中B因子含量及变化分析

Analysis of abnormality expression of B factor in serum of patients with systemic crthematosus

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【作者】 刘敏万建新曾智杰俞纯山

【Author】 LIU Min ;WAN Jian-Xin; ZENG Zhi-Jie; YU Chun-Shan (The first Affiliated Hospital of Yi-xian Sun Medical University, Guangzhou 510080)

【机构】 中山医科大学附属第一医院检验科!广州510080

【摘要】 为了了解系统性红斑狼疮患者血清中补体(C3、C4及B因子)在疾病的发病及进程中的仓量变化及其关系。采用速率散射比法法对红斑狼疮活动期与稳定期患者各50例血清中的补体C3、C4及B因子进行检测。结果显示;活动期C3、C4及B因子降低均有极显著意义(P<0.001);稳定期C3、C4含量虽有所回升但与对照组相比仍有显著降低(P<0.001),而B因子基本回复到正常水平(P>0,05)。认为,血清中补体含量在整个病程的降低可作为系统性红斑狼疮患者诊断的免疫学依据,而B因子在疾病稳定后最早回复正常这一特点,可作为判断病期及疗效观察的有用指标。

【Abstract】 Objective In order to know the conditions of complement in patients of SLE and the relation with disease process, rate nphelometyr was used to detected C3, C4 and B factor to each of 50 patients in active and steady SLE. Result:C3, C4 still were significantly lower in recome normal level. Conclusions: Determination of complement can provide basis for immunifaction appraisal and monitor of SLE. The characteristic that B factor recome to normal level early when disease steady can use it as effective immune target in diagnosis and curative observation.

  • 【文献出处】 陕西医学检验 ,SHAAXI JOURNAL OF MEDICAL LABORATORY SCIENCES , 编辑部邮箱 ,1999年03期
  • 【分类号】R593.241
  • 【被引频次】5
  • 【下载频次】23
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