【摘要】 甲型肝炎病毒TZ84毒株经 2BS二倍体细胞培养制备成甲型肝炎灭活疫苗。采用普通狨猴和恒河猴进行疫苗的保护性研究。结果均有较好的抗体反应 ,而且对甲型肝炎病毒鲁兴株 (强毒株 )的攻击亦均有保护作用。表明该疫苗有较好的免疫效果。更多还原

【Abstract】 Inactivated hepatitis A(HA) vaccine was prepared by culturing the strain TZ84 of HA virus in 2BS cells, and the immunogencity of it was studied in common marmosets and Macaca mulattas. The result showed that good antibody respones were induced in the 2 kinds of monkeys. The vaccine could also protect the monkeys from the challenge with strong virus strain(Luxing). It indicated that the inactivated HA vaccine had good immunological effect.\;更多还原