【摘要】 在中性生物碱饱和特性模型的基础上，引入膜电位的影响，考虑生物碱阳离子通量对总生物碱扩散通量的影响，从而导出膜电位影响的饱和特性模型。将模型在特定参数下积分，对实验结果进行数值模拟，结果表明，所建模型可很好描述各种生物碱（高ｐＫａ值和低ｐＫａ值生物碱）的跨膜传递过程，为建立描述生物碱跨膜传递过程的普适性模型提供了理论基础更多还原

【Abstract】 The saturation model with the influence of membrane potential is set up on the basis of neutral alkaloid saturation model, with the effect of membrane potential on the flux of alkaloid cation. Comparing the simulating results with the experimental ones, it demonstrates that the model can describe the transport phenomenon across cell membrane of any alkaloid (with low pKa and high pKa value). These provide theoretical basis for an universal model describing the transport phenomenon.更多还原