【摘要】 目的　分析我院前列腺癌诊断现状，以提高前列腺癌的早期诊断水平。方法　１９８８ ～１９９８ 年收治１３０ 例前列腺癌病人，分别通过直肠指检（ Ｄ Ｒ Ｅ） 、前列腺抗原（ Ｐ Ｓ Ａ） 、前列腺穿刺活检、 Ｂ超、 Ｃ Ｔ、 Ｅ Ｃ Ｔ、 Ｍ Ｒ、膀胱镜检查等明确诊断。结果　直肠指检示前列腺增大，质地坚硬或触及结节１１２例（８６ ．２ ％ ） 。 Ｐ Ｓ Ａ＜ ４ｎｇ／ｍｌ ６ 例（４ ．６ ％ ） ， Ｐ Ｓ Ａ ４ ～１０ｎｇ／ ｍｌ １６ 例（１２ ．３ ％ ） ， Ｐ Ｓ Ａ＞ １０ｎｇ／ｍｌ １０８ 例（８３ ．１ ％ ） 。 Ｐ Ｓ Ａ＜ ２０ｎｇ／ｍｌ 发生骨转移４ 例， Ｐ Ｓ Ａ＞ ４０ｎｇ／ ｍｌ 发生骨转移４６ 例。前列腺穿刺活检阳性１０１／１０８ 例（９３ ．５ ％ ） 。经腹部 Ｂ 超诊断符合率５５ ．１ ％ ，经直肠 Ｂ 超诊断符合率９４ ．７ ％ ， Ｃ Ｔ、 Ｍ Ｒ 诊断符合率４２ ．９ ％ ， Ｅ Ｃ Ｔ 诊断符合率８１ ．３ ％ 。病理分期为 Ｃ 和 Ｄ 期９５ 例（７５ ．３） ％ ，３５ 例为 Ａ 和 Ｂ 期（２４ ．７ ％ ） 。结论　前列腺癌的早期诊断仍是一个急待解决的问题；开展有关前列腺癌宣教工作、定期专科体检和增强特定人群的就诊意识，将提高前列腺癌的早期诊断率。更多还原

【Abstract】 Objective Analyzing the present status of diagnosis of prostatic cancer in our department so as to improve early detection of this disease. Methods 130 cases of prostatic cancer were diagnosed by digital rectal examination (DRE), serum prostatic antigen (PSA), transrectal echography of prostate (TRUS), prostatic biopsy, CT, ECT, MR and cystoscopy.Results Among the 130 patients, 112 cases (86.2%) were positive by DRE. There were 6 cases (4.6%) whose PSA were<4ng/ml, 16 cases (12.3%) PSA 4～10ng/ml, 108 cases (83.1%) PSA>10ng/ml. In the patients whose PSA<20ng/ml, 4 cases already were detected with bone metastasis, but in those with PSA>40ng/ml, 46 cases had bone metastasis. Of 108 cases of prostatic biopsy, 101 (93.5%) were positive. The detective rate of transrectal ultrasound screening was 94.7%, transabdominal ultrasound screening 55.1%, CT、MR 42.9%, ECT 81.3%. 95 cases (75.3%) were stage of C and D and 35 cases (24.7%) were stage A and B.Conclusion Early detection of prostatic cancer is still a question to be solved. Propagating knowledge of prostatic di sease, seeking medical advice and examined by specialist timely after 50 years of age might increase early diagnostic rate.(Shanghai Med J, 1999,22∶515 517)更多还原